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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3034 details
Primary information
Hemolytik ID3034
PMID19038369
YEAR2009
SEQUENCEILPWKWPWWPWRR
LENGTH13
NAMEID
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicCyclic
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY10% hemolysis at 100μg/mL
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCCSSCSSCC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1g89A NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEIndolicidin-derived antimicrobial peptide analogs with greater bacterial selectivity and requirements for antibacterial and hemolytic activities.
AUTHORSKim SM,Kim JM,Joshi BP,Cho H
JOURNALBiochim Biophys Acta. 2009 Feb;1794(2):185-92. doi: 10.1016/j.bbapap.2008.10.009. Epub 2008 Nov 6.