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2988 details
Primary information
Hemolytik ID2988
PMID22082130
YEAR2011
SEQUENCEKLAKKLAKLAKLAKAL
LENGTH16
NAMEModelin-5-CONH2
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY<2% hemolytic at 300μM
RBCs SOURCEPig
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTHHHHHHHHHHTTTC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEEffect of cholesterol on the membrane interaction of Modelin-5 isoforms.
AUTHORSDennison SR
JOURNALBiochemistry. 2011 Dec 20;50(50):10898-909. doi: 10.1021/bi201267v. Epub 2011 Nov 21.