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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2979 details
Primary information
Hemolytik ID2979
PMID22040603
YEAR2011
SEQUENCEGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR
LENGTH32
NAMECrp4-wt
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY3.4% hemolytic at 25μg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCCSSCCCCCCCSSCCCCTTSCSCCCCCC
SMILESNCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1tv0A NA NA P28311
from
61
TO
92		 NA NA NA NA
Reference Informaiton
ARTICLEBiosynthesis and antimicrobial evaluation of backbone-cyclized ?-defensins.
AUTHORSGarcia AE,Tai KP,Puttamadappa SS,Shekhtman A,Ouellette AJ
JOURNALBiochemistry. 2011 Dec 6;50(48):10508-19. doi: 10.1021/bi201430f. Epub 2011 Nov 9.