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2967 details
Primary information
Hemolytik ID2967
PMID21955251
YEAR2011
SEQUENCEGIIKKIIKKIIKKIIKKI
LENGTH18
NAMEG(IIKK)4I
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial and Antitumor
ACTIVITYEC50 = 41±2μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCGGGGTTHHHHHHHGGGC
SMILESNCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEDesigned antimicrobial and antitumor peptides with high selectivity.
AUTHORSHu J,Chen C,Zhang S,Zhao X,Xu H,Zhao X
JOURNALBiomacromolecules. 2011 Nov 14;12(11):3839-43. doi: 10.1021/bm201098j. Epub 2011 Oct 3.