Primary information |
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Hemolytik ID | 2962 |
PMID | 21820306 |
YEAR | 2011 |
SEQUENCE | tle-k-tle-A-tle-A-tle-A |
LENGTH | 8 |
NAME | C |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Cyclic |
Stereochemistry | Mix (Contains both L and D amino acids) |
Modified Residues | Tle=Tert-leucine |
FUNCTION | Antimicrobial |
ACTIVITY | No hemolytic at 1000μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | NA |
SMILES | NA |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
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Reference Informaiton |
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ARTICLE | Pharmacodynamic synergy strictly dependent on the co-operative aggregation of enantiomers of cyclic peptides in the bacterial cell membrane. |
AUTHORS | Danielsson M,Rosenthal-Aizman K,Bergsson G |
JOURNAL | Bioorg Med Chem Lett. 2011 Sep 15;21(18):5262-5. doi: 10.1016/j.bmcl.2011.07.032. Epub 2011 Jul 19. |