Primary information |
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Hemolytik ID | 2951 |
PMID | 21801309 |
YEAR | 2011 |
SEQUENCE | SWLRDIWDWLCELLSDFK |
LENGTH | 18 |
NAME | I10L/V13L |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Anti-HCV/HIV |
ACTIVITY | MHC =3.44μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSSGGGGGGCCSSSCCC |
SMILES | N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Rational design of peptides with anti-HCV/HIV activities and enhanced specificity. |
AUTHORS | Li GR,He LY,Liu XY,Liu AP,Huang YB,Qiu C,Zhang XY,Xu JQ,Yang W |
JOURNAL | Chem Biol Drug Des. 2011 Nov;78(5):835-43. doi: 10.1111/j.1747-0285.2011.01201.x. Epub 2011 Sep 26. |