Primary information |
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Hemolytik ID | 2911 |
PMID | 21607695 |
YEAR | 2011 |
SEQUENCE | FKCRRWQWRMKKLGAPSITCVRRAF |
LENGTH | 25 |
NAME | LfcinB (C–C) |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | ~7% hemolytic at 256mg/ml |
RBCs SOURCE | Pig |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCCCHHHHTTSSCCCCGGGGGCC |
SMILES | N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
1lfcA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
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Reference Informaiton |
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ARTICLE | Comparative antimicrobial activity and mechanism of action of bovine lactoferricin-derived synthetic peptides. |
AUTHORS | Liu Y,Han F,Xie Y |
JOURNAL | Biometals. 2011 Dec;24(6):1069-78. doi: 10.1007/s10534-011-9465-y. Epub 2011 May 24. |