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2911 details
Primary information
Hemolytik ID2911
PMID21607695
YEAR2011
SEQUENCEFKCRRWQWRMKKLGAPSITCVRRAF
LENGTH25
NAMELfcinB (C–C)
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY~7% hemolytic at 256mg/ml
RBCs SOURCEPig
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCCHHHHTTSSCCCCGGGGGCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1lfcA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEComparative antimicrobial activity and mechanism of action of bovine lactoferricin-derived synthetic peptides.
AUTHORSLiu Y,Han F,Xie Y
JOURNALBiometals. 2011 Dec;24(6):1069-78. doi: 10.1007/s10534-011-9465-y. Epub 2011 May 24.