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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2854 details
Primary information
Hemolytik ID2854
PMID21335383
YEAR2011
SEQUENCEKKlFKKILKYL
LENGTH11
NAMEBP144
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY7±0.4% hemolytic at 250μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTHHHHHHHHC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEImprovement of the efficacy of linear undecapeptides against plant-pathogenic bacteria by incorporation of D-amino acids.
AUTHORSGuell I,Cabrefiga J,Badosa E,Ferre R,Talleda M,Bardaji E,Planas M,Feliu L
JOURNALAppl Environ Microbiol. 2011 Apr;77(8):2667-75. doi: 10.1128/AEM.02759-10. Epub 2011 Feb 18.