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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2827 details
Primary information
Hemolytik ID2827
PMID21300831
YEAR2011
SEQUENCEGKKllKKlKKllKKG
LENGTH15
NAMEMA-d
C-ter ModificationAmidation
N-ter ModificationAcetylation
Linear/CyclicLinear
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY1% hemolytic at 3.4mg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTTTHHHHHHHGGGC
SMILESNCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEBioactivity and the first transmission electron microscopy immunogold studies of short de novo-designed antimicrobial peptides.
AUTHORSAzad MA,Huttunen-Hennelly HE
JOURNALAntimicrob Agents Chemother. 2011 May;55(5):2137-45. doi: 10.1128/AAC.01148-10. Epub 2011 Feb 7.