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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2801 details
Primary information
Hemolytik ID2801
PMID20858205
YEAR2011
SEQUENCEkwksflktfksakktvlhtllkaiss
LENGTH26
NAMED2
C-ter ModificationAmidation
N-ter ModificationAcetylation
Linear/CyclicLinear
StereochemistryD
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYHC50 =83μg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHHHTTSSTTGGGHHHHHHHCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O.C(C)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEAnti-tuberculosis activity of ?-helical antimicrobial peptides: de novo designed L- and D-enantiomers versus L- and D-LL-37.
AUTHORSJiang Z,Higgins MP,Whitehurst J,Kisich KO,Voskuil MI
JOURNALProtein Pept Lett. 2011 Mar;18(3):241-52.