| Primary information |
|---|
| Hemolytik ID | 2795 |
| PMID | 20848624 |
| YEAR | 2010 |
| SEQUENCE | fP-Ada-GO-Ada-AfP-Ada-GO-AdaA |
| LENGTH | 10 |
| NAME | GS6 |
| C-ter Modification | Free |
| N-ter Modification | Free |
| Linear/Cyclic | Cyclic |
| Stereochemistry | Mix (Contains both L and D amino acids) |
| Modified Residues | Ornithine, Ada=Adamantylalanine |
| FUNCTION | Antimicrobial |
| ACTIVITY | HC50 =7.55±1.10μM |
| RBCs SOURCE | Human |
| Secondary information |
|---|
| Properties | Physico-Chemical details |
| STRUCTURE | |
| DSSP states | NA |
| SMILES | NA |
| External Links |
|---|
| PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
| NA |
NA |
NA |
NA |
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| Reference Informaiton |
|---|
| ARTICLE | An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity. |
| AUTHORS | Kapoerchan VV,Knijnenburg AD,Niamat M,Spalburg E,de Neeling AJ,Nibbering PH,Mars-Groenendijk RH,Noort D,Otero JM,Llamas-Saiz AL,van Raaij MJ,van der Marel GA,Overkleeft HS |
| JOURNAL | Chemistry. 2010 Oct 25;16(40):12174-81. doi: 10.1002/chem.201001686. |
