Primary information |
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Hemolytik ID | 2786 |
PMID | 20798581 |
YEAR | 2010 |
SEQUENCE | GWGSFFKKAAHVGKHVGKAALTHYL |
LENGTH | 25 |
NAME | Ple |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 7% hemolytic at 100μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCHHHHTTTHHHHHHHTSGGGSCCC |
SMILES | NCC(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
1z64A |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
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Reference Informaiton |
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ARTICLE | Influence of the hydrophobic amino acids in the N- and C-terminal regions of pleurocidin on antifungal activity. |
AUTHORS | Lee J |
JOURNAL | J Microbiol Biotechnol. 2010 Aug;20(8):1192-5. |