Primary information |
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Hemolytik ID | 2781 |
PMID | 20058937 |
YEAR | 2010 |
SEQUENCE | KKllKKLkKlLK |
LENGTH | 12 |
NAME | C6-K7L5 |
C-ter Modification | Amidation |
N-ter Modification | Acetylation (CH3(CH2)4CO) |
Linear/Cyclic | Linear |
Stereochemistry | Mix (Contains both L and D amino acids) |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 0% hemolytic at 100μM (non-hemolytic) |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CTTHHHHHHHTC |
SMILES | N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. |
AUTHORS | Rosenfeld Y,Lev N |
JOURNAL | Biochemistry. 2010 Feb 9;49(5):853-61. doi: 10.1021/bi900724x. |