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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2712 details
Primary information
Hemolytik ID2712
PMID22391524
YEAR2012
SEQUENCEGWLDVAKKIGKAAFNVAKNFL
LENGTH21
NAMEMON
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYHC50 =37.3±1.4μmol/L
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHHHHHHHHHHHTTSCC
SMILESNCC(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEEffects of dimerization on the structure and biological activity of antimicrobial peptide Ctx-Ha.
AUTHORSLorenzon EN, Cespedes, G ,Cespedes GF, Vicente, E ,Vicente EF,Nogueira LG,Bauab TM,Castro MS
JOURNALAntimicrob Agents Chemother. 2012 Jun;56(6):3004-10. doi: 10.1128/AAC.06262-11. Epub 2012 Mar 5.