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2708 details
Primary information
Hemolytik ID2708
PMID22371493
YEAR2012
SEQUENCEMGIIAGIIKVIKSLIEQFTGK
LENGTH21
NAMEPSMα1
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONImmunosuppressive and Antimicrobial
ACTIVITY58% hemolytic at 10μg/mL
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTHHHHHHHHHHTTGGGTTTC
SMILESN[C@@H](CCSC)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P0C7X8 NA G7ZRU2 NA NA NA
Reference Informaiton
ARTICLENovel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry.
AUTHORSGonzalez DJ,Okumura CY,Hollands A,Kersten R,Akong-Moore K,Pence MA,Malone CL,Derieux J,Moore BS,Horswill AR,Dixon JE,Dorrestein PC
JOURNALJ Biol Chem. 2012 Apr 20;287(17):13889-98. doi: 10.1074/jbc.M112.349860. Epub 2012 Feb 27.