Primary information |
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Hemolytik ID | 2674 |
PMID | 23652359 |
YEAR | 2013 |
SEQUENCE | KIGAKIKIGAKIKIGAKI |
LENGTH | 18 |
NAME | KIGAKI-wt |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | ~54% hemolytic at 60μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSEESSSSEEECSSSCC |
SMILES | N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes. |
AUTHORS | Wadhwani P,Reichert J,Strandberg E,Burck J,Misiewicz J,Afonin S,Heidenreich N,Fanghanel S,Mykhailiuk PK,Komarov IV |
JOURNAL | Phys Chem Chem Phys. 2013 Jun 21;15(23):8962-71. doi: 10.1039/c3cp50896j. Epub 2013 May 7. |