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2673 details
Primary information
Hemolytik ID2673
PMID23652359
YEAR2013
SEQUENCEKIGAKIKIGAKIKIGAKI
LENGTH18
NAMEKIGAKI-wt
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY~14% hemolytic at 7.5μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSEESSSSEEECSSSCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEStereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes.
AUTHORSWadhwani P,Reichert J,Strandberg E,Burck J,Misiewicz J,Afonin S,Heidenreich N,Fanghanel S,Mykhailiuk PK,Komarov IV
JOURNALPhys Chem Chem Phys. 2013 Jun 21;15(23):8962-71. doi: 10.1039/c3cp50896j. Epub 2013 May 7.