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2599 details
Primary information
Hemolytik ID2599
PMID23344198
YEAR2013
SEQUENCELLKKLLKWLKK
LENGTH11
NAMEL5K5W 8
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial and Hemolytic
ACTIVITYMHC =128μg/mL
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHHHHTTC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEStructural characterization of de novo designed L5K5W model peptide isomers with potent antimicrobial and varied hemolytic activities.
AUTHORSKim SJ,Kim JS,Lee YS,Sim DW,Lee SH,Bahk YY,Lee KH,Kim EH,Park SJ,Lee BJ
JOURNALMolecules. 2013 Jan 11;18(1):859-76. doi: 10.3390/molecules18010859.