Primary information |
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Hemolytik ID | 2591 |
PMID | 23519707 |
YEAR | 2013 |
SEQUENCE | GLFDIIKKIAESFKFSEAIKKIIDFLG |
LENGTH | 27 |
NAME | (AU)2K |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 10% hemolytic at 4μmol/L |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CGGGHHHHHHHHCSSTHHHHGGGTTCC |
SMILES | NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)/C/1=N/[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)OO1 |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Dimerization of aurein 1.2: effects in structure, antimicrobial activity and aggregation of Cândida albicans cells. |
AUTHORS | Lorenzon EN,Sanches PR,Nogueira LG,Bauab TM |
JOURNAL | Amino Acids. 2013 Jun;44(6):1521-8. doi: 10.1007/s00726-013-1475-3. Epub 2013 Mar 22. |