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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2581 details
Primary information
Hemolytik ID2581
PMID23570790
YEAR2013
SEQUENCEWKSYVRRWRS
LENGTH10
NAMETSG-9
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY-0.4 ± 0.5%hemolytic at 100μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCGGGGTCCCC
SMILESN[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEStructure-activity relationship of potent antimicrobial peptide analogs of Ixosin-B amide.
AUTHORSWu YS,Liao ZJ,Wang KS
JOURNALBioorg Med Chem Lett. 2013 May 15;23(10):2929-32. doi: 10.1016/j.bmcl.2013.03.053. Epub 2013 Mar 25.