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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2570 details
Primary information
Hemolytik ID2570
PMID23609760
YEAR2013
SEQUENCEFVDLKKIANIINSIFGK
LENGTH17
NAMETemporin-1CEa
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial and Anticancer and moderate Hemolytic
ACTIVITYLC50 =95.7μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCHHHHHHHHHHHTCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA B8QP36
from
48
TO
64
NA NA
Reference Informaiton
ARTICLEDesign of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa.
AUTHORSYang QZ,Wang C,Lang L,Zhou Y,Wang H
JOURNALArch Pharm Res. 2013 Apr 23.