Primary information |
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Hemolytik ID | 2570 |
PMID | 23609760 |
YEAR | 2013 |
SEQUENCE | FVDLKKIANIINSIFGK |
LENGTH | 17 |
NAME | Temporin-1CEa |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial and Anticancer and moderate Hemolytic |
ACTIVITY | LC50 =95.7μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCHHHHHHHHHHHTCC |
SMILES | N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
NA |
NA |
NA |
B8QP36 from 48 TO 64 |
NA |
NA |
|
Reference Informaiton |
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ARTICLE | Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa. |
AUTHORS | Yang QZ,Wang C,Lang L,Zhou Y,Wang H |
JOURNAL | Arch Pharm Res. 2013 Apr 23. |