Home Page
   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

This page displays user query in tabular form.

2537 details
Primary information
Hemolytik ID2537
PMID10673369
YEAR1999
SEQUENCEKWCFCVCYRGICYCRCRG
LENGTH18
NAMEcc TP
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYEC25 =590μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCBCTTSSBSSCCCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEMarked increase in membranolytic selectivity of novel cyclic tachyplesins constrained with an antiparallel two-beta strand cystine knot framework.
AUTHORSTam JP,Lu YA
JOURNALBiochem Biophys Res Commun. 2000 Jan 27;267(3):783-90.