Primary information |
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Hemolytik ID | 2518 |
PMID | 10973820 |
YEAR | 2000 |
SEQUENCE | GEKLKKIGQKIKKFFQKL |
LENGTH | 18 |
NAME | K13-CRAMP-18 |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial and Anticancer |
ACTIVITY | 0% hemolytic at 100μM (non-hemolytic) |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCHHHHHHHHHHGGGGGC |
SMILES | NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | CRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity. |
AUTHORS | Shin SY,Kang SW,Lee DG,Eom SH,Song WK |
JOURNAL | Biochem Biophys Res Commun. 2000 Sep 7;275(3):904-9. |