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2502 details
Primary information
Hemolytik ID2502
PMID14965277
YEAR2004
SEQUENCEGWGSFFKKAAHVGKHVGKAALTHYL
LENGTH25
NAMEPle
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY2.5% hemolytic at 100μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHTTTHHHHHHHTSGGGSCCC
SMILESNCC(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1z64A NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEEffects of two glycine residues in positions 13 and 17 of pleurocidin on structure and bacterial cell selectivity.
AUTHORSLim SS,Song YM,Jang MH,Kim Y,Hahm KS
JOURNALProtein Pept Lett. 2004 Feb;11(1):35-40.