Primary information |
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Hemolytik ID | 2499 |
PMID | 15222751 |
YEAR | 2004 |
SEQUENCE | GVVTDLLKTAGKLLGNLVGSLSG |
LENGTH | 23 |
NAME | [K8,12] – DRP-PD 3-6 |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Cytotoxic |
ACTIVITY | 71% hemolytic at 100μM |
RBCs SOURCE | Rat |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCHHHHTTTHHHHHTTTSCCCCC |
SMILES | NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
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Reference Informaiton |
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ARTICLE | Membrane association, electrostatic sequestration, and cytotoxicity of Gly-Leu-rich peptide orthologs with differing functions. |
AUTHORS | Vanhoye D,Bruston F,El Amri S,Ladram A,Amiche M |
JOURNAL | Biochemistry. 2004 Jul 6;43(26):8391-409. |