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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2492 details
Primary information
Hemolytik ID2492
PMID15222751
YEAR2004
SEQUENCEGLVTSLIKGAGKLLGGLFGSVTGGQS
LENGTH26
NAMEDRP-PBN2
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONCytotoxic
ACTIVITY42% hemolytic at 50μM
RBCs SOURCERat
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHHTTSSTTTSSSCCCCCCSCC
SMILESNCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA Q800R4
from
45
TO
70
NA NA
Reference Informaiton
ARTICLEMembrane association, electrostatic sequestration, and cytotoxicity of Gly-Leu-rich peptide orthologs with differing functions.
AUTHORSVanhoye D,Bruston F,El Amri S,Ladram A,Amiche M
JOURNALBiochemistry. 2004 Jul 6;43(26):8391-409.