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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2435 details
Primary information
Hemolytik ID2435
PMID10795591
YEAR2000
SEQUENCEKWCFRVCYRGICYRRCR
LENGTH17
NAMETP-1
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY66.5% hemolysis at 80µg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSCCCCSSSCCCTTCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1ma2A NA P69136 NA NA NA NA NA
Reference Informaiton
ARTICLEEvaluation of the inactivation of infectious Herpes simplex virus by host-defense peptides.
AUTHORSYasin B,Pang M,Turner JS,Cho Y,Dinh NN,Waring AJ,Lehrer RI
JOURNALEur J Clin Microbiol Infect Dis. 2000 Mar;19(3):187-94.