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2401 details
Primary information
Hemolytik ID2401
PMID12878508
YEAR2003
SEQUENCEWLNALLHHGLNCAKGVLA
LENGTH18
NAME18Hc
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial
ACTIVITY~20% hemolysis at 100µg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHTTSSTTSSCCCCC
SMILESN[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P83705 NA NA NA NA NA
Reference Informaiton
ARTICLEBiological activities of synthetic analogs of halocidin, an antimicrobial peptide from the tunicate Halocynthia aurantium.
AUTHORSJang WS,Kim CH,Kim KN,Park SY,Lee JH,Son SM
JOURNALAntimicrob Agents Chemother. 2003 Aug;47(8):2481-6.