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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2400 details
Primary information
Hemolytik ID2400
PMID15369808
YEAR2004
SEQUENCEILGKIWKIKKLF
LENGTH12
NAME[K7, P8, K11]-IsCT
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial and Antifungal
ACTIVITY0% hemolysis at 100µM (non-hemolytic)
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTTSSSCCCSCC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEAntibiotic activity and structural analysis of the scorpion-derived antimicrobial peptide IsCT and its analogs.
AUTHORSLee K,Shin SY,Kim K,Lim SS,Hahm KS
JOURNALBiochem Biophys Res Commun. 2004 Oct 15;323(2):712-9.