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2389 details
Primary information
Hemolytik ID2389
PMID15546886
YEAR2005
SEQUENCEGCRFCCNCCPNMSGCGVCCRF
LENGTH21
NAMEBass Hepcidin
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial and Antifungal
ACTIVITY0% hemolysis at 100 µg/ml (non-hemolytic)
RBCs SOURCERat
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCSSSSSCCSCCSSSSCC
SMILESNCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1s6wA NA NA P82951
from
65
TO
85
NA Q0R3J5
from
65
TO
85
NA NA
Reference Informaiton
ARTICLEBass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections.
AUTHORSLauth X,Babon JJ,Stannard JA,Singh S,Nizet V,Carlberg JM,Ostland VE,Pennington MW,Norton RS
JOURNALJ Biol Chem. 2005 Mar 11;280(10):9272-82. Epub 2004 Nov 16.