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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2329 details
Primary information
Hemolytik ID2329
PMID15019213
YEAR2003
SEQUENCEAKKVFKRLEKLFSKIQNDK
LENGTH19
NAMEHP (2–20)
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial and Antifungal
ACTIVITY<20% hemolysis at 2.15 to 215µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHTTTHHHHSGGGSCC
SMILESN[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1p0gA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEPrevention of lethal murine candidiasis using HP (2-20), an antimicrobial peptide derived from the N-terminus of Helicobacter pylori ribosomal protein L1.
AUTHORSRibeiro PD
JOURNALPeptides. 2003 Nov;24(11):1807-14.