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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2283 details
Primary information
Hemolytik ID2283
PMID12681513
YEAR2003
SEQUENCEKKFPWWWPFKK
LENGTH11
NAMESYM11KK
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY0% hemolysis at 200μg/ml (non-hemolytic)
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCTTCCSCCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLESelective cytotoxicity following Arg-to-Lys substitution in tritrpticin adopting a unique amphipathic turn structure.
AUTHORSYang ST,Shin SY,Lee CW,Kim YC,Hahm KS
JOURNALFEBS Lett. 2003 Apr 10;540(1-3):229-33.