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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2210 details
Primary information
Hemolytik ID2210
PMID12207877
YEAR2002
SEQUENCEVRRFPFFFPFLRR
LENGTH13
NAMETWF
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial and Antifungal
ACTIVITY0% hemolysis at 200µg/ml (non-hemolytic)
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCTTTTCCCCTTC
SMILESN[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEConformation-dependent antibiotic activity of tritrpticin, a cathelicidin-derived antimicrobial peptide.
AUTHORSYang ST,Yub Shin SY,Kim YC,Kim Y,Hahm KS
JOURNALBiochem Biophys Res Commun. 2002 Sep 6;296(5):1044-50.