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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2209 details
Primary information
Hemolytik ID2209
PMID12207877
YEAR2002
SEQUENCEVRRFAWWWAFLRR
LENGTH13
NAMETPA
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial and Antifungal
ACTIVITY~ 90% hemolysis at 200µg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSCHHHHHHHTC
SMILESN[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2i1fA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEConformation-dependent antibiotic activity of tritrpticin, a cathelicidin-derived antimicrobial peptide.
AUTHORSYang ST,Yub Shin SY,Kim YC,Kim Y,Hahm KS
JOURNALBiochem Biophys Res Commun. 2002 Sep 6;296(5):1044-50.