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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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2202 details
Primary information
Hemolytik ID2202
PMID12110678
YEAR2002
SEQUENCELLkKLlKllLKLlKK
LENGTH15
NAMEAmphipathic-2D
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesNone
FUNCTIONAntibacterial
ACTIVITY0% hemolysis at 100µM (non-hemolytic)
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHHHHHHHHCCC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEThe consequence of sequence alteration of an amphipathic alpha-helical antimicrobial peptide and its diastereomers.
AUTHORSPapo N,Oren Z,Pag U,Sahl HG
JOURNALJ Biol Chem. 2002 Sep 13;277(37):33913-21. Epub 2002 Jul 10.