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2179 details
Primary information
Hemolytik ID2179
PMID11932493
YEAR2002
SEQUENCEKNLRRIIRKGIHIIKKYG
LENGTH18
NAMENovispirin G-10
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY1.8% hemolysis at 40µg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTHHHHGGGGGCCCCCCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1hu6A NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEImpact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides.
AUTHORSSawai MV,Waring AJ,Kearney WR,McCray PB Jr,Forsyth WR,Lehrer RI, Tack, Brian ,Tack B
JOURNALProtein Eng. 2002 Mar;15(3):225-32.