Primary information |
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Hemolytik ID | 2174 |
PMID | 12005420 |
YEAR | 2001 |
SEQUENCE | KWKLFKKIPLKKF |
LENGTH | 13 |
NAME | C-9 |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antibacterial |
ACTIVITY | 6.2% hemolysis at 100µM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSCCCCCCCCCC |
SMILES | N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. |
AUTHORS | Shin SY,Lee SH,Yang ST,Park EJ,Lee DG,Lee MK,Eom SH,Song WK,Kim Y,Hahm KS |
JOURNAL | J Pept Res. 2001 Dec;58(6):504-14. |