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2112 details
Primary information
Hemolytik ID2112
PMID11279030
YEAR2001
SEQUENCEWLGSALKIGAKLLPSVVGLFKKKKQ
LENGTH25
NAMEPonericin-W1
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial and Insecticidal
ACTIVITYZone of inhibition (1 mm) at 0.4-0.5mM
RBCs SOURCESheep
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCTHHHHTTHHHHHHHHHHHCCC
SMILESN[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P82423 NA NA NA NA NA
Reference Informaiton
ARTICLEPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii.
AUTHORSOrivel J,Redeker V,Le Caer JP, Krier, ,Krier F,Revol-Junelles AM,Longeon A,Chaffotte A,Dejean A
JOURNALJ Biol Chem. 2001 May 25;276(21):17823-9. Epub 2001 Feb 22.