Primary information |
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Hemolytik ID | 2109 |
PMID | 11168895 |
YEAR | 2000 |
SEQUENCE | GWGSFFKKAAAVGKAVGKAALTAYL |
LENGTH | 25 |
NAME | [A11,15,23]Ple |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antibacterial |
ACTIVITY | 45% hemolysis at 100µM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CTTHHHHTTHHHHHHHHHHHTTTCC |
SMILES | NCC(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity. |
AUTHORS | Yoshida K,Mukai Y,Niidome T,Takashi C,Tokunaga Y,Hatakeyama T |
JOURNAL | J Pept Res. 2001 Feb;57(2):119-26. |