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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2100 details
Primary information
Hemolytik ID2100
PMID11168895
YEAR2000
SEQUENCEGWGSFFKKAAHVGKHVGKAALTHYL
LENGTH25
NAMEPleurocidin
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial
ACTIVITY6% hemolysis at 100µM
RBCs SOURCERabbit
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHTTTHHHHHHHTSGGGSCCC
SMILESNCC(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1z64A NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEInteraction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity.
AUTHORSYoshida K,Mukai Y,Niidome T,Takashi C,Tokunaga Y,Hatakeyama T
JOURNALJ Pept Res. 2001 Feb;57(2):119-26.