Primary information |
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Hemolytik ID | 2080 |
PMID | 22426384 |
YEAR | 2012 |
SEQUENCE | GIFSLFKAGAKFFGKHLLKQAGKAGAEHLACKATNQC |
LENGTH | 37 |
NAME | Esculentin-2LTa |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | LD50 >600µM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSSHHHHHHHHHHHHHHTTGGGGSTHHHHSSSSCCC |
SMILES | NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
NA |
NA |
NA |
B9W1Q0 from 40 TO 76 |
NA |
NA |
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Reference Informaiton |
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ARTICLE | Molecular cloning and characterization of antimicrobial peptides from skin of the broad-folded frog, Hylarana latouchii. |
AUTHORS | Wang H,Yu Z,Hu Y,Yu H,Ran R,Xia J,Wang D,Yang S,Yang X |
JOURNAL | Biochimie. 2012 Jun;94(6):1317-26. doi: 10.1016/j.biochi.2012.02.032. Epub 2012 Mar 8. |