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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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2080 details
Primary information
Hemolytik ID2080
PMID22426384
YEAR2012
SEQUENCEGIFSLFKAGAKFFGKHLLKQAGKAGAEHLACKATNQC
LENGTH37
NAMEEsculentin-2LTa
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYLD50 >600µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSSHHHHHHHHHHHHHHTTGGGGSTHHHHSSSSCCC
SMILESNCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA B9W1Q0
from
40
TO
76
NA NA
Reference Informaiton
ARTICLEMolecular cloning and characterization of antimicrobial peptides from skin of the broad-folded frog, Hylarana latouchii.
AUTHORSWang H,Yu Z,Hu Y,Yu H,Ran R,Xia J,Wang D,Yang S,Yang X
JOURNALBiochimie. 2012 Jun;94(6):1317-26. doi: 10.1016/j.biochi.2012.02.032. Epub 2012 Mar 8.