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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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2018 details
Primary information
Hemolytik ID2018
PMID10667861
YEAR2000
SEQUENCELKLASIVSWAKKVL
LENGTH14
NAME[Ala4]MP-B
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY60.1% hemolysis at 50µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCHHHHHHHTTC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLERelationship between the tertiary structures of mastoparan B and its analogs and their lytic activities studied by NMR spectroscopy.
AUTHORSYu K,Kang S,Park N,Shin J
JOURNALJ Pept Res. 2000 Jan;55(1):51-62.