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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1995 details
Primary information
Hemolytik ID1995
PMID15003829
YEAR2004
SEQUENCEFLSLALAALPKLFCLIFKKC
LENGTH20
NAMEBrevinin-1PRa
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYHC50 =7µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHHTTTTTTTSSSSCCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA P0C5W7
from
47
TO
66		 NA A0AAS2
from
48
TO
67		 NA NA
Reference Informaiton
ARTICLEA family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica.
AUTHORSConlon JM,Sonnevend A,Patel M,Al-Dhaheri K, Nielsen, Per ,Nielsen PF,Kolodziejek J,Nowotny N,Iwamuro S
JOURNALRegul Pept. 2004 May 15;118(3):135-41.