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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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1984 details
Primary information
Hemolytik ID1984
PMID11520071
YEAR2001
SEQUENCEILGKIWEGIKSLF
LENGTH13
NAMEIsCT
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONCytotoxic
ACTIVITY50-60% hemolysis at 100µM
RBCs SOURCESheep
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSTHHHHTTCCC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1t51A NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEIsCT, a novel cytotoxic linear peptide from scorpion Opisthacanthus madagascariensis.
AUTHORSDai L,Yasuda A,Naoki H,Corzo G,Andriantsiferana M
JOURNALBiochem Biophys Res Commun. 2001 Aug 31;286(4):820-5.