| Primary information |
|---|
| Hemolytik ID | 1979 |
| PMID | 11478963 |
| YEAR | 2001 |
| SEQUENCE | LKLkSIVSWAKKVL |
| LENGTH | 14 |
| NAME | [D-Lys4]-MP-B |
| C-ter Modification | Amidation |
| N-ter Modification | Free |
| Linear/Cyclic | Linear |
| Stereochemistry | Mix (Contains both L and D amino acids) |
| Modified Residues | None |
| FUNCTION | Hypotensive |
| ACTIVITY | 5% hemolysis at 15µM |
| RBCs SOURCE | Guinea-pig |
| Secondary information |
|---|
| Properties | Physico-Chemical details |
| STRUCTURE | |
| DSSP states | CCCCHHHHHHTTTC |
| SMILES | N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O |
| External Links |
|---|
| PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
| NA |
NA |
P21654 |
NA |
NA |
NA |
36940 |
NA |
|
| Reference Informaiton |
|---|
| ARTICLE | Enhancing the hypotensive effect and diminishing the cytolytic activity of hornet mastoparan B by D-amino acid substitution. |
| AUTHORS | Ho CL,Shih YP,Wang KT |
| JOURNAL | Toxicon. 2001 Oct;39(10):1561-6. |
