Primary information |
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Hemolytik ID | 1974 |
PMID | 11478963 |
YEAR | 2001 |
SEQUENCE | LKLKSIVSWAKKVL |
LENGTH | 14 |
NAME | MP-B |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Hypotensive |
ACTIVITY | ~95% hemolysis at 20µM |
RBCs SOURCE | Guinea-pig |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCHHHHHHTTTC |
SMILES | N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
P21654 |
NA |
NA |
NA |
36940 |
NA |
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Reference Informaiton |
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ARTICLE | Enhancing the hypotensive effect and diminishing the cytolytic activity of hornet mastoparan B by D-amino acid substitution. |
AUTHORS | Ho CL,Shih YP,Wang KT |
JOURNAL | Toxicon. 2001 Oct;39(10):1561-6. |