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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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1973 details
Primary information
Hemolytik ID1973
PMID11478963
YEAR2001
SEQUENCELKLKSIVSWAKKVL
LENGTH14
NAMEMP-B
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONHypotensive
ACTIVITY~85% hemolysis at 15µM
RBCs SOURCEGuinea-pig
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCHHHHHHTTTC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P21654 NA NA NA 36940 NA
Reference Informaiton
ARTICLEEnhancing the hypotensive effect and diminishing the cytolytic activity of hornet mastoparan B by D-amino acid substitution.
AUTHORSHo CL,Shih YP,Wang KT
JOURNALToxicon. 2001 Oct;39(10):1561-6.