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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1928 details
Primary information
Hemolytik ID1928
PMID17961502
YEAR2008
SEQUENCERLEKLFSKIQNDK
LENGTH13
NAMEHPN3(8–20)
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY0% hemolysis at 100µM (non-hemolytic)
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHHSGGGGCC
SMILESN[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA 1p0gA
from
7
TO
19
NA NA NA NA NA NA
Reference Informaiton
ARTICLEAmphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions.
AUTHORSPark SC,Kim MH,Hossain MA,Shin SY,Kim Y,Stella L,Wade JD,Park Y
JOURNALBiochim Biophys Acta. 2008 Jan;1778(1):229-41. Epub 2007 Oct 2.