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1872 details
Primary information
Hemolytik ID1872
PMID15196144
YEAR2004
SEQUENCEDSHEKRHHGYKRKFHEKHHSHRGY
LENGTH24
NAMEHistatin-5
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntifungal
ACTIVITY0% hemolysis at 100µM (non-hemolytic)
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSSCCSSSCCSCSSCSSSCCSCC
SMILESN[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@H]1CCC(=O)OOC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCCN)Cc1[nH]cnc1)Cc1[nH]cnc1)CO)Cc1[nH]cnc1)CCCN=C)Cc1ccccc1
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEFungicidal effect of three new synthetic cationic peptides against Candida albicans.
AUTHORSNikawa H,Fukushima H,Makihira S,Hamada T
JOURNALOral Dis. 2004 Jul;10(4):221-8.