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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1816 details
Primary information
Hemolytik ID1816
PMID17826814
YEAR2007
SEQUENCEELAGTIIDGASLTFEVLDKVLGELGKVSRK
LENGTH30
NAMESt I 2–31
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONHemolytic
ACTIVITYHemolytic activity expresssed as the initial rate (∆A/∆t, min-1) i.e. at above 100
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSTTSCCSSSSCHHHHHHHTCHHHHSCCC
SMILESN[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLECorrelations between differences in amino-terminal sequences and different hemolytic activity of sticholysins.
AUTHORSCilli EM,Pigossi FT,Crusca E Jr,Ros U,Martinez D,Lanio ME,Alvarez C
JOURNALToxicon. 2007 Dec 15;50(8):1201-4. Epub 2007 Aug 3.